The TP53 gene is a gene that is mutated in many cancers. It is the most common gene mutation found in cancer cells. A tumor-suppressor gene, TP53 codes for a protein that inhibits the development and ...

This complex process, known as gene expression, determines which proteins we make and whether we make them in the correct amounts, crucial work given that proteins play a role in virtually every a ...

In 2020, we wrote about why there were only 11 cell and gene therapies in Europe. A bit over four years later, there are 20 – almost twice as many. But is it such a big improvement? Take a look ...

Gene expression is the generation of a functional gene product from the information encoded by a gene, through the processes of transcription and translation. Gene products are often proteins ...

An in vivo base editing approach targeting the PRNP gene led to a 52% increase in the lifespan of mouse models inoculated with the most common sporadic and genetic types of human pathogenic prion ...

Comparison of gene expression differences between pericyte clusters and all other clusters using ... Transcription factors significantly highly expressed in these six pericyte subpopulations were ...

NHS patients with sickle cell disease will be able to benefit from a groundbreaking gene-editing treatment that offers the prospect of a cure for the condition. The one-off gene therapy, known as ...

The Basketball Coaches Association of Michigan released Monday its fourth set of boys hoops rankings for the 2024-25 season, and new No. 1 teams have emerged in three of the state’s four ...

The rankings only include teams whose head coaches are BCAM members, which is what allowed Detroit U-D Jesuit to take the top spot in Division 1, after being left off the poll last week.

Asiawu Imam says the therapy will make a huge difference A gene-editing therapy for sickle cell disease, with a price tag of £1.65m, is to be offered to patients on the NHS in England.

The same is now possible in gene editing. Rather than employ separate tools for editing genes and regulating their expression, these distinct goals can now be combined into a single tool that can ...

The first human trial of insulin-producing cells that have been gene-edited to evade immune attack is a success so far. The cells have survived and produced insulin for a month after being ...