Atypical lymphocytes that survive genetic damage likely undergo more mutations. Clonal expansion of these mutated cells may subsequently promote their progression into malignant lymphomas.

Feb. 4, 2025 — Research has shown that a potential new targeted therapy for childhood brain cancer is effective in infiltrating and killing tumor cells in preclinical models tested in mice.

Stem cells are cells that have the capacity to self-renew by dividing and to develop into more mature, specialised cells. Stem cells can be unipotent, multipotent, pluripotent or totipotent ...

Background/Aim: To determine the roles of gastroesophageal acid reflux (GER) and esophageal dysmotility on typical and atypical GERD symptoms. Methods: Two hundred thirty-six patients (159 females ...

Natural killer (NK) cells are the predominant innate lymphocyte subsets that mediate anti-tumor and anti-viral responses, and therefore possess promising clinical utilization. NK cells do not express ...

Feb. 18, 2025 — Viruses, like those that cause COVID-19 or HIV, are formidable opponents once they invade our bodies. Antiviral treatments strive to block a virus or halt its replication ...

Background Atypical carcinoids (AC) of the lung are rare intermediate-grade neuroendocrine neoplasms. Prognostic factors for these tumours are undefined. Methods Our cooperative group retrieved data ...

Although neurons are considered the basic units of the brain and nervous system, they do not do all the work. Glia are a non-neuronal category of cells that do not transmit electrical signals but ...

Background While p53 mutations occur early in Barrett’s oesophagus (BE) progression to oesophageal adenocarcinoma (EAC), their role in gastric cardia stem cells remains unclear. Objective This study ...

Methods: Single-cell RNA sequencing on placental decidua was performed to reveal the immune disturbances landscape at the MFI in preeclampsia. Human Jar cells and NK-92MI cells were employed to study ...

Bladder cancer occurs when cancerous cells form in the tissues of the bladder, the hollow organ in your abdomen that stores urine. The bladder has several layers, and cancer cells can form in any ...