Symptoms such as premature fatigue and exertional myalgia are usually seen within minutes of moderate to high intensity activity, when defective anaerobic glycolysis results in failure of energy ...

Furthermore, mTORC2 activation is also implied in metabolic regulation as it is involved in the repression of the FoxO3, a transcriptional factor that is responsible for the inhibition of the ...

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Ox-LDL, oxidized low-density lipoprotein; SR-A1, scavenger receptor class A type 1; CE, cholesterol ester; FA, fatty acid; FC, free cholesterol; LAL, lysosomal acid lipase; HDL, high-density ...

We see the seven stones of the Molecular Systems Biology cover as a visual allegory for Aristotle's visionary thought: The whole is greater than the sum of its parts.

RNA-seq and MS analyses indicated that L-arginine switched glycolysis to oxidative phosphorylation in inflammatory osteoclasts leading to increased ATP production, purine metabolism and elevated ...

Absence of muscle glycogen phosphorylase results in the inability to mobilise muscle glycogen stores. This poses a problem to patients with McArdle disease when there is a need for anaerobic ...