Analysts at Jefferies have suggested the first-in-class ATP citrate lyase (ACL) inhibitor could achieve peak sales in the region of $2-$3 billion, again depending on a cardiovascular outcomes ...

Background The mechanisms of ACL injury in rugby are not well defined. Aim To describe the mechanisms of ACL injury in male professional rugby players using systematic video analysis. Methods 36 cases ...

Nexletol (bempedoic acid) was approved as an alternative to statins in 2020 as the first drug in the ATP Citrate Lyase (ACL) inhibitor class, and was once tipped as a future blockbuster ...

If you are a sports enthusiast, particularly a footballer or a gymnast, you're likely to have heard about an ACL injury. The Anterior Cruciate Ligament (ACL) is a ligament in the knee that ...

Data sources Seven databases were searched in December 2021. Eligibility criteria Observational or interventional studies with self-reported activity (including return to sport) or knee-related ...

Chitinase inhibitors are gaining attention as a promising strategy for pest control in agriculture. These inhibitors target chitinases, enzymes that play a crucial role in the growth and ...

Treatment strategies in the management of FH have investigated the potential role of certain additional options, including microsomal transfer protein inhibitors, liver-selective thyroid hormone ...

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