and BMS-303141), BMS-303141 had the highest affinity for ACL and reduced ACL expression in the kidneys of db/db mice. We reported that BMS-303141 administration could decrease the levels of serum ...

Engineered enzymes are poised to have transformative impacts across applications in energy, materials, biotechnology, and medicine. Recently, machine learning has emerged as a useful tool for ...

Dear W.R.: Finasteride works by blocking the enzyme that converts regular testosterone to dihydrotestosterone (DHT). DHT is ...

Elevated liver enzymes can occur for many reasons. Most often, elevated liver enzymes are temporary and resolve on their own without treatment. Occasionally, elevated liver enzymes require additional ...

Enzyme mechanisms are the chemical transformations, and the steps within them, generated by enzymatic action on substrates. The mechanism of enzyme catalysis is similar in principle to other types ...

It is a unique member of the plastic family as it can be broken down into its constituent units (or monomers) by PETases, which are enzymes that degrade PET. Until now, scientists have discovered ...

Thraustochytrid is a promising algal oil resource with the potential to meet the demand for docosahexaenoic acid (DHA). However, oils with high DHA content produced by genetic modified ...

Data sources Seven databases were searched in December 2021. Eligibility criteria Observational or interventional studies with self-reported activity (including return to sport) or knee-related ...

I am an 88-year-old male who has been taking tamsulosin twice daily for several years because of benign prostatic hyperplasia (BPH). In October 2023, my urologist added finasteride once daily. One ...

I am an 88-year-old male who has been taking tamsulosin twice daily for several years because of benign prostatic hyperplasia ...

The following observations show that this coagulation is due to the presence of an enzyme in goat semen. The enzyme is present in plasma and requires activation by calcium ; hence absence or delay ...