The availability of large-scale protein-protein interaction data has led to the recent popularity of the study of protein interaction networks. Just as the enormous amount of available sequence ...

The identification of protein interactions has been greatly simplified by the invention of yeast-based screening assays such as the yeast two-hybrid system. However, yeast two-hybrid assays cannot ...

enabling scientists to engineer novel protein-protein interactions that play key roles in cell regulation and therapeutics. A year and a half later, the team has reported -- again in Nature-- an ...

Two new studies represent a big step toward developing innovative molecular therapies capable of disrupting the ...

A Cornell University-led collaboration has uncovered the equipment that enables bacteria to survive exposure to antibiotics: ...

A novel geometric deep learning framework designs ligand-specific protein binders, enhancing therapeutic potential in cell therapies and synthetic biology.

Our research focuses on studies on the molecular structure and mechanism of proteins, recently mostly on the endoplasmic reticulum proteins involved in cellular stress signalling, including in ...

Jumbo phages utilize a complex protein import system, with Imp1 as a key gatekeeper, to transport proteins into their ...

Although powerful, microarray chips did not provide any information about the proteins bound to the DNA and how they might affect gene expression. To uncover the sites of protein-DNA interactions at ...

This sequence ultimately dictates the protein's three-dimensional structure and function. Proteins often interact with other proteins to form complexes or networks that carry out specific biological ...

Vimentin is a type III intermediate filament (IF) protein normally expressed in cells that develop into connective tissue, ...