What's the difference between mRNA and pre-mRNA? It's all about splicing of introns ... and joined to the 5′ end. This step occurs by transesterification; in this case, an OH group at the ...

What's the difference between mRNA and pre-mRNA? It's all about splicing of introns. See how one RNA sequence can exist in nearly 40,000 different forms.

Research into splicing mechanisms and patterns is essential for decerning fundamental biological principles, as well as clarifying the molecular basis of many diseases and developing new therapies. 2 ...

These findings highlight the integrative role of nuclear speckles in coordinating transcription, splicing and 3′ end formation. "Pre-mRNA 3′ end processing is a critical step in mRNA ...