In the past decade, high-throughput structure determination with X-ray crystallography has demonstrated its value as a tool not just for optimizing lead compounds, but also for lead discovery.
The X-ray crystallography laboratory in the School of Mathematical and Physical Sciences is both a user and service facility. We are equipped with three single crystal and two powder diffractometers.
All of the single crystal diffractometers are equipped with modern kappa-geometry goniometers. Two of these have conventional fixed Mo-anode X-ray tubes and are used for routine samples. The third is ...
X-Ray Crystallography The new knowledge of the atomic structure of matter uncovered over the past half-century by the X-ray-diffraction technique has led to a fundamental revision of ideas in many ...
The X-ray Crystallography Center was fully renovated in November 2007 and houses a single-crystal X-ray diffraction system, a brand-new Bruker D8 VENTURE diffractometer, providing X-ray diffraction ...
Assistance with grant writing and manuscript preparation is also offered. Training: Training is available for unassisted use of the crystallization robot, imager and X-ray machine. Crystallization ...
Ramakrishnan, a distinguished structural biologist and Nobel Laureate in Chemistry (2009), is renowned for his groundbreaking ...
Jon Mason and Miles Congreve from Heptares will describe what protein-ligand X-ray data can do for your medicinal chemistry project. How these data can be interpreted and used to influence both the ...
Our analytical XRD instrument utilises X-ray radiation to investigate the structure of crystallised biomolecular assemblies through X-ray diffraction (XRD). X-ray radiation is a type of ionising ...
The XtaLAB MM003 is equipped with a MicroMax-003 Microfocus sealed tube X-ray generator system, an AFC11 Partial-χ 4-axis goniometer, a Dectris PILATUS 200K 2D hybrid pixel array detector, and an ...
Concept Life Sciences, a UK-based drug discovery specialist, has joined forces with Accelero Biostructures, a US-based leader in X-ray crystallography, to accelerate early drug discovery. This ...