We have described the clinical manifestations of isotretinoin (ISO) neuroembryopathy (J Ped, 105, 595, 1984) and with others have suggested that disturbances in neural crest development may ...

The risk for acne relapse following isotretinoin use is reduced with higher cumulative doses, suggesting individualized treatment plans based on patients’ goals could maximize efficacy ...

It is pivotal to understand whether certain factors, such as patient characteristics, isotretinoin dosage, and treatment regimen, influence acne relapse. This information can be used to design ...

These indications remain outside the current product license. Over the years, isotretinoin has also been used 'off-license' to treat several other conditions with variable success, including ...

Because many clinicians prescribe a topical retinoid or benzoyl peroxide to use for a while after isotretinoin therapy completion, he continued, “I wonder if the study could be expanded to ...

Isotretinoin, commonly referred to as Accutane, is the only approved medical treatment capable of inducing long-term remission of severe acne. Although highly effective, some individuals ...

Of the 19,907 patients, 35% received a subsequent prescription acne treatment, with 22.5% receiving an oral medication; 8.2% were treated with a second course of isotretinoin.

They found that acne recurrence necessitating treatment with oral medication such as oral antibiotics, spironolactone, or another course of isotretinoin occurred in approximately 1-in-5 patients ...