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However, you must be careful not to exceed the maximum daily dose. An overdose of Tylenol can cause liver toxicity that could ...

Is it safe to take acetaminophen? Yes, it's usually safe when taken according to the directions on the label. But taking more than that can cause liver damage, liver failure, or even death.

The maximum safe dosage of acetaminophen for most people over the age of 12 years is 4,000 milligrams (mg) per day. But, even this amount may harm your liver if you have a chronic condition.