Furthermore, NFTs may also contribute to the disease progression by effectively sequestering more tau and other proteins, and thereby reinforcing and amplifying the loss of normal tau function.

are neurobiological lesions that are found in brain cells of patients with Alzheimer's disease (AD). They consist of aggregates of abnormally phosphorylated tau proteins that are altered in ...

Tau is a protein that builds up and moves between nerve cells in the brains of people living with Alzheimer’s disease, causing damage. Professor Mudher is using clever genetic manipulation in fruit ...

Taking longer to drift into the dreaming phase – known as rapid eye movement (REM) sleep – could be an early sign of ...

Despite promising results in animal models, the study found no significant reduction in the tau protein among participants with early-stage Alzheimer’s disease who were treated with nicotinamide ...

A large number of studies over the past 20 years have quantified phosphorylated tau protein in the cerebrospinal fluid of people with Alzheimer’s disease, consistently finding that levels of tau ...

The team reported that the treatment has significantly cleared tau protein build-up and enhanced cognitive functioning among mice with neurodegenerative diseases. So, according to the researchers ...

Now, a new study by researchers at the University of Pittsburgh adds more evidence to the link between Alzheimer’s disease and HSV-1. Their new research has also revealed how tau protein may ...

A characteristic feature of AD is the presence of neurofibrillary tangles, primarily composed of hyperphosphorylated tau protein ... including Pick's disease, progressive supranuclear palsy ...

While the precise mechanisms by which HSV-1 influences tau protein and contributes to Alzheimer’s disease are still unknown, Shemesh and his colleagues plan to explore those questions in future ...

this protein has been found to contribute to some neurodegenerative diseases, broadly defined as tauopathies. Specifically, past research linked the levels of tau in the brains of patients ...