Researchers have identified a method to enhance the effectiveness of a promising cancer treatment. They found that modifying ...

such as T cells and B cells. Brain cancer and other nervous system cancers have a 33.4% five-year survival rate. In adults, brain tumors rarely begin in the brain — when they do, they're known ...

In this article, Cerba dives into CAR+ T-cell therapy, from patient treatment to solutions for minimal residual disease (MRD) ...

T cells are white blood cells that are important for adaptive immunity. They have unique cell surface receptors that are generated by randomly assorting genes. These receptors allow T cells to ...

Researchers have revolutionized cancer immunotherapy by developing a way to grow T cells in the lab that live longer and ...

Researchers found that bioengineered CAR-T cells when mixed with other immune cells can "donate" proteins, suggesting ...

Pathogen-fighting immune cells called tissue-resident memory CD8 T cells (TRM cells) go through a surprising transformation -- and relocation -- as they fight infections in the small intestine.

Fate Therapeutics uses iPSC and gene editing to offer scalable off-the-shelf therapies. Read more to see why I rate FATE ...

In this study, researchers aimed to understand how CAR T cells with different signaling domains work at the molecular and cellular levels to lay the foundation for designing CAR molecules that ...

CD8+ T-cells exhibit disease-promoting and disease-regulating functions in inflammatory diseases. In fact, previous studies have reported that granzyme B (GZMB)-expressing CD8+ T-cells have induce ...

Engineered immune cells called CAR-T cells are used in the treatment of cancer. Researchers from Uppsala University have now ...

and activation of HLA-B-restricted T cells, thereby serving clues for T1D onset. TRIM28 is known to recruit chromatin modifiers to its target regions to co-regulate gene expression in multiple ...