Low-grade squamous intraepithelial lesions (LSILs) found in a Pap smear ... appear to have a risk of being concerning or cancerous, treatment involves exercising or removing the abnormal tissue.

Lipid or immunohistochemical stains may be necessary to differentiate between squamous intraepithelial neoplasia and intraepithelial spread of sebaceous gland carcinoma. Treatment. The treatment ...