Our DNA is constantly under threat — from cell division errors to external factors like sunlight and smoking. Fortunately, ...

More information: Yoshiki Ochiai et al, SUPREM: an engineered non-site-specific m6A RNA methyltransferase with highly improved efficiency, Nucleic Acids Research (2024). DOI: 10.1093/nar/gkae887 ...

A new review article highlights the transformative role of circular RNA (circRNA) in cancer, revealing its potential as both a key player in tumor biology and a promising avenue for future therapies.

A new review article highlights the transformative role of circular RNA (circRNA) in cancer, revealing its potential as both a key player in tumor ...

A new review article highlights the transformative role of circular RNA (circRNA) in cancer, revealing its potential as both ...

N6-methyladenosine (m6A) is one such mechanism, where methyl groups are added to the N6 position of adenosine on RNA. Adding these methyl groups enhances RNA stability; however, their removal by ...

study hypothesis states that the pathological features of IHD are mirrored in circulating cellular or extracellular epitranscriptomes. The study focuses on m6A modifications as well as A-to-I editing ...

They say that change takes time. Well, that's not the case for RNA. The small biological molecule acts like a switchboard operator, capable of changing its shape every few milliseconds so it can ...