Our DNA is constantly under threat — from cell division errors to external factors like sunlight and smoking. Fortunately, ...

More information: Yoshiki Ochiai et al, SUPREM: an engineered non-site-specific m6A RNA methyltransferase with highly improved efficiency, Nucleic Acids Research (2024). DOI: 10.1093/nar/gkae887 ...

A new review article highlights the transformative role of circular RNA (circRNA) in cancer, revealing its potential as both a key player in tumor biology and a promising avenue for future therapies.

A new review article highlights the transformative role of circular RNA (circRNA) in cancer, revealing its potential as both a key player in tumor ...

study hypothesis states that the pathological features of IHD are mirrored in circulating cellular or extracellular epitranscriptomes. The study focuses on m6A modifications as well as A-to-I editing ...

N6-methyladenosine (m6A) is one such mechanism, where methyl groups are added to the N6 position of adenosine on RNA. Adding these methyl groups enhances RNA stability; however, their removal by ...