直接RNA测序(DRS)技术 ... CXCL10 mRNA的稳定性通过YTHDF1介导的m6A位点识别维持。 pum6a不仅扩展了m 6 Anet的功能,还通过整合电信号和碱基配对特征 ...
2021 年,一篇题为“Small RNAs are modified with N - glycans and displayed on the surface of living cells”的论文在 Cell 期刊上发表,首次向科学界揭示了糖基化 RNA (GlycoRNA)的存在。自此,围绕 RNA 糖基化的相关研究迅速成为热点,在标记技术、监测方法以及生物功能探究等方面不断取得新的突破, ...
2. circRNA的作用机制多样,包括充当miRNA“海绵”、编码蛋白质,以及与RNA结合蛋白相互作用 ... 5. 研究还发现circSTX6存在m6A修饰,METTL3介导其m6A甲基 ...
N 6-甲基腺苷 (m 6 A)是目前在不同物种中研究最为广泛的RNA修饰,m 6 A修饰在免疫系统中的重要作用已经被充分揭示,包括了mRNA代谢、细胞分化、增殖 ...
RNA 2'-氧-甲基化广泛分布在rRNA和m RNA上, 具有重要的功能, 由于检测方法的局限, 其研究仍具有挑战。为深入理解该领域, 本文全面综述了RNA2'-氧-甲基化的分布、检测方法、功能以及疾病中的作用和治疗潜力。导 ...
Binding of both the RNA-binding protein TDP-43 and the m6A RNA modification chemical tag has been found to be altered in genes that are dysregulated in HD. Further, TDP-43 pathology, classically ...
Binding of both the RNA-binding protein TDP-43 and the m6A RNA modification chemical tag has been found to be altered on genes that are dysregulated in HD. Further, TDP-43 pathology, classically ...
Binding of both the RNA-binding protein TDP-43 and the m6A RNA modification chemical tag has been found to be altered on genes that are dysregulated in HD. Further, TDP-43 pathology, classically ...