In most recent advancements, RNA editing uses the CRISPR-Cas13 system, a newer technique that was created specifically to help develop therapies that work with RNA. DNA editing is permanent, which ...

But sometimes, the body can make small edits to these instructions—this is where RNA editing comes in. RNA editing is like a ...

Editing RNA isn’t all that different from DNA base-editing techniques, which typically use Cas9 or other enzymes attached to a CRISPR guide RNA to replace one nucleotide with another. In the case of ...

Mammalian RNAs can be edited by the conversion of adenosine to inosine, which is read as guanosine, but technological constraints have limited our view of the overall contribution of RNA editing ...

Shares in Wave Life Sciences rose by 74% after it reported clinical data with a pioneering new RNA-editing therapy for alpha-1 antitrypsin deficiency (AATD). Wave claims this is the first clinical ...

This new tool, known as minimal, versatile genetic perturbation technology (mvGPT), combines the powers of gene editing, ...

Akribion Therapeutics emerges from stealth with €8 million in seed funding to develop a novel cancer RNA-guided approach ...

The company’s innovative approach using the Axiomer RNA editing platform to address this genetic driver is promising, with plans to commence clinical testing of their PNPLA3-targeted candidate ...

If it can be copied accurately in human cells, the RNA programmability of this new biological mechanism could eventually allow complex gene editing that could cure genetic diseases that carry ...

Over the years, scientists have explored alternatives to Cas9, such as Cas12a for more precise multigene editing, a type III CRISPR for RNA editing, and a Cas13 loaded with multiple guide RNAs for ...

By studying this amazing structure, how did scientists learn about RNA editing? The first tools developed for the study of cells and tissues were optical microscopes. These microscopes use visible ...