Figure 1: Secondary structures of RNA stem-loops that bind to MS2 coat ... Figure 3: Close up of the GA non-Watson-Crick base pair in the F5 aptamer complex structure with the final aptamer ...

Overview of RNA repair – There is an emerging appreciation of the existence of “RNA repair” pathways that rely on RNA ligases to maintain or manipulate RNA structure in response to purposeful RNA ...

Researchers have now uncovered the 3D structure of the RNA enzyme SAMURI. Their study provides insights into the development of ribozymes and the evolution of catalytically active RNA. Researchers ...

Inosine can be incorporated into primers and probes as a universal base due to its ability to pair with multiple nucleotides ... and structural biology approaches will provide a more comprehensive ...

and several nitrogen-containing bases. Later it was found that the sugar in nucleic acid can be ribose or deoxyribose, giving two forms: RNA and DNA. In 1943, American Oswald Avery proved that DNA ...

In plants, secondary and tertiary RNA structures, such as G-quadruplexes ... and low-translation-associated motifs based on their base pair characteristics. High-translation motifs had balanced ...

The chemical structure of uracil, showing its single-ring pyrimidine structure ... RNA-based therapies, such as small interfering RNA (siRNA) and antisense oligonucleotide (ASOs), rely on the specific ...

Both the sequence of bases and the three-dimensional structure of RNA are determining factors in the great versatility of functions that characterize the molecule. The team used the mechanical ...