Scientists at the Faculty of Medicine have now developed an innovative numbering system for the GAIN domain, a protein domain common to all adhesion GPCRs. It should help to elucidate the role of ...
Representatives from four leading companies highlight emerging basic and clinical research that drives renewed optimism.
When faced with chronic stress, why do some people develop anxiety and depressive symptoms while others show resilience? A ...
Supercomputer simulations have revealed how changes in the shape of the HIV-1 capsid protein may help the virus squeeze its inner core into the host cell's nuclear membrane. The findings, by a ...
Now, the Phox homology (PX) domain, an evolutionarily conserved protein domain whose function has so far been elusive, has been demonstrated to bind phosphoinositides. The interactions of PX ...
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Insights into mechanosensitive aGPCRs and their role in biological processes and diseaseThis newly published analysis in Genes & Diseases sheds light on the crucial role of mechanosensitive adhesion G protein-coupled receptors (aGPCRs) in regulating biological processes and their ...
Researchers investigating the role of the protein CD44 in obesity and metabolic health found that CD44-deficient mice stayed ...
Recent studies showed that a peptide, the protein transduction domain (PTD) from HIV Tat, could improve the distribution of cytoplasmic reporter proteins when administered systemically as fusion ...
Northwestern University researchers have identified structural features in engineered cell receptors that correlate with ...
Alcober-Boquet L; Zang T; Pietsch L; Suess E; Hartmann M; Proschak E; Gross LZF; Sacerdoti M; Zeuzem S; Rogov VV; Leroux AE; Piiper A; Biondi RM ...
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