Now, the Phox homology (PX) domain, an evolutionarily conserved protein domain whose function has so far been elusive, has been demonstrated to bind phosphoinositides. The interactions of PX ...

Scientists at the Faculty of Medicine have now developed an innovative numbering system for the GAIN domain, a protein domain common to all adhesion GPCRs. It should help to elucidate the role of ...

When the COVID-19 pandemic first began, we saw how quickly the SARS-CoV-2 virus evolved. New variants emerged with mutations ...

Recent studies showed that a peptide, the protein transduction domain (PTD) from HIV Tat, could improve the distribution of cytoplasmic reporter proteins when administered systemically as fusion ...

When faced with chronic stress, why do some people develop anxiety and depressive symptoms while others show resilience? A ...

Supercomputer simulations have revealed how changes in the shape of the HIV-1 capsid protein may help the virus squeeze its inner core into the host cell's nuclear membrane. The findings, by a ...

Integrating best practices in AI, genomics, cell culture, and laboratory techniques together contribute to protein expression success.

However, the intricate mechanisms governing these processes have remained elusive due to the presence of multiple functional domains within Munc13, each playing distinct roles in neurotransmitter ...

Northwestern University researchers have identified structural features in engineered cell receptors that correlate with ...

Using protein structure prediction tools, researchers have uncovered receptor structure-function relationships to improve cell therapies.

Researchers investigating the role of the protein CD44 in obesity and metabolic health found that CD44-deficient mice stayed ...