The intake of aspartame was studied in 51 adults 23 of whom were carriers for phenylketonuria (PKU). The study was divided into a loading test followed by chronic intake for a period of 12 weeks.

Novel enzyme therapy will treat adults with PKU who have uncontrolled blood phenylalanine concentrations with current treatment. The US Food and Drug Administration (FDA) has approved biotech ...

Novel enzyme therapy will treat adults with PKU who have uncontrolled blood phenylalanine concentrations with current treatment. The US Food and Drug Administration (FDA) has approved biotech ...

Genetic disease characterized by mental retardation, light skin, and eczema; caused by mutations in the gene that encodes phenylalanine hydroxylase (PAH), a liver enzyme that normally metabolizes ...

Treatment for PKU is relatively straightforward. In the U.S., all babies are tested for PKU at birth. These babies are placed on special diets low in phenylalanine until they are about 5 years old.

The study demonstrated that PKU GOLIKE, administered as the last daily dose and compared to standard amino acid protein substitutes, improved metabolic control by reducing harmful phenylalanine (Phe) ...

Scientists and clinicians have historically categorized PKU as a problem with the gene that encodes the enzyme phenylalanine hydroxylase (PAH), which converts the amino acid phenylalanine into ...

The study demonstrated that PKU GOLIKE, administered as the last daily dose and compared to standard amino acid protein substitutes, improved metabolic control by reducing harmful phenylalanine ...

1 Department of Medicine, NUTH NHS Foundation Trust, Newcastle Upon Tyne, UK 2 Directorate of Women's Services, NUTH NHS Foundation Trust, Newcastle Upon Tyne, UK Background Neonatal screening and ...