Novel enzyme therapy will treat adults with PKU who have uncontrolled blood phenylalanine concentrations with current treatment. The US Food and Drug Administration (FDA) has approved biotech ...

Medically reviewed by Allison Herries, RDN L-tyrosine is an amino acid that's often used in supplements to improve cognitive ...

Genetic disease characterized by mental retardation, light skin, and eczema; caused by mutations in the gene that encodes phenylalanine hydroxylase (PAH), a liver enzyme that normally metabolizes ...

We analyzed mutations, RFLP haplotypes (H), and a VNTR polymorphism at the phenylalanine hydroxylase locus (PAH) in 12 French-Canadian patients with phenylketonuria (PKU) from the eastern region ...

The study demonstrated that PKU GOLIKE, administered as the last daily dose and compared to standard amino acid protein substitutes, improved metabolic control by reducing harmful phenylalanine ...

The study demonstrated that PKU GOLIKE, administered as the last daily dose and compared to standard amino acid protein substitutes, improved metabolic control by reducing harmful phenylalanine (Phe) ...

Scientists and clinicians have historically categorized PKU as a problem with the gene that encodes the enzyme phenylalanine hydroxylase (PAH), which converts the amino acid phenylalanine into ...

Phenylketonuria (PKU) is a genetic metabolic disorder that increases levels of the essential amino acid known as phenylalanine in the blood. People with PKU are unable to metabolize phenylalanine ...

Aspartame contains an amino acid known as phenylalanine. Persons with PKU cannot metabolize phenylalanine and, undetected and unaddressed, the condition can cause significant health problems.

The study demonstrated that PKU GOLIKE, administered as the last daily dose and compared to standard amino acid protein substitutes, improved metabolic control by reducing harmful phenylalanine ...