Ultraviolet (UV) radiation from the sun is a well-known cause of DNA damage, which can lead to diseases like skin cancer. But ...

The Summit supercomputer revealed how damaged strands of DNA are surgically repaired by a molecular pathway called nucleotide ...

Sunburns and aging skin are obvious effects of exposure to harmful UV rays, tobacco smoke and other carcinogens. But the ...

Two new studies show how a seeming tangle of DNA is actually organized into a structure that coordinates thousands of genes ...

A new structural blueprint paves the way for improved targeting of cancer cells, particularly those with BRCA1 and BRCA2 ...

Two new landmark studies show how a seeming tangle of DNA is actually organized into a structure that coordinates ... proximity junctions where far-flung parts of the genome are paired up next ...

Each ODN in the Takumi-shaped DNA structure was constructed with an eight-18 nucleotide-long palindromic stem attached to two cohesive parts on either side with a thymidine (T) spacer. The ODNs ...

Two new studies uncover how DNA folding controls sperm cell development. Researchers identified proteins that rearrange ...

Although previous studies have mapped parts of Pol-theta’s structure, the enzyme’s interactions with DNA weren’t well understood. “What’s been missing is how Pol-theta actually engages ...

Scientists at Scripps Research have now captured the first detailed images of the DNA repair protein, Pol-theta, in action, ...

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these ...