We have established that the uptake of BCG by bladder cancer cells is through macropinocytosis rather than phagocytosis. Entry of BCG into bladder cancer cells is dependent on Rac1, Cdc42, and the ...

This cellular contortion is a process called macropinocytosis. Blocking it and cutting off the energy and protein building blocks it provides has been shown to significantly suppress tumor growth.

This cellular contortion is a process called macropinocytosis. Blocking it and cutting off the energy and protein building blocks it provides has been shown to significantly suppress tumor growth.

The main focus of the laboratory is to understand how cells perform macropinocytosis – the bulk capture of extracellular fluid. This plays important and distinct roles in diverse cell types such as ...

New research from the Craig Thompson Lab offers a closer look at the transcriptional activators, Yap/Taz, and the role they play in cell growth and macropinocytosis. King, B., Araki, J., Palm, W., & ...