A knockout mouse is a laboratory mouse in which one or more genes have been turned off or "knocked out." To create a knockout mouse, scientists genetically engineer the animal by disrupting a gene ...
Anxiety disorders, characterized by an excessive apprehension about real or perceived threats and dysfunctional behaviors aimed at avoiding these threats, are among the most common mental health ...
It’s a new way to create “bi-paternal” mice that can survive to adulthood—but human applications are still a long way off.
Researchers find that certain antioxidant enzymes, called selenoproteins, significantly contribute to fighting cell aging. The team used a gene knockout mouse model to help them study the effects of ...
Many foods are often advertised for their antioxidant properties. Antioxidants counteract what are known as reactive oxygen ...
Researchers develop a novel Tle6 gene hetero knockout mice model to understand the role of this gene in male fertility and find that its deficiency results in abnormal sperm structure, reduced ...
They followed by isolating EVs from normal mice and knockout mice lacking the gene that encodes the BK potassium channel, and found the cargo in EVs from the knockout mice were very different in ...
They followed by isolating EVs from normal mice and knockout mice lacking the gene that encodes the BK potassium channel, and found the cargo in EVs from the knockout mice were very different in ...
Myocardial fibrosis is a key process for heart failure development that may lead to severe phenotypes, including cardiac arrest or sudden death. Vasorin (VASN) is a protein with high expression in the ...
The Knockout Mouse Phenotyping Program (KOMP2) sites at Baylor College of Medicine, Jackson Laboratory, and University of California, Davis, are collaborating with the International Mouse Phenotyping ...
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