Without the second gene copy to worry about, we can generate these knockout cell lines in a fairly streamlined and convenient fashion — and we can hit pretty much any gene in the genome.

In theory, mutating a gene of interest inside stem cells enables researchers to analyze the effects of that mutation on the development of particular cell types. In the laboratory of Jack Parent at ...

Many foods are often advertised for their antioxidant properties. Antioxidants counteract what are known as reactive oxygen ...

Researchers find that certain antioxidant enzymes, called selenoproteins, significantly contribute to fighting cell aging. The team used a gene knockout mouse model to help them study the effects of ...