1). Current AF therapies include several ion channel blockers that have proarrhythmic potential by non-discriminating interactions with ion channels in the heart. Because CKD-510 does not directly ...

Today it seems self-evident that neurons make their electrical signals by opening gates of water-filled pores (ion channels) in the plasma membrane. But it was not always so. Remarkably ...

In 2004, a research group at Peking University First Hospital discovered a mutation in the gene coding for a sodium-channel subunit in individuals with a rare and serious disorder called inherited ...