More information: Maryam Kazerani et al, Histone methyltransferase SETDB1 safeguards mouse fetal hematopoiesis by suppressing activation of cryptic enhancers, Proceedings of the National Academy ...

In this context, a comment by Chen et al. provides valuable insights into the catalytic and noncatalytic functions of the histone methyltransferase SETD2, a protein responsible for histone H3 ...

Yushenova further demonstrated that bdelloids possess a histone methyltransferase that preferentially recognizes 4mC marks on DNA, using them to steer its methylation of histones. The two ...

These include DNA methyltransferase and histone deacetylase (HDAC) inhibitors. Further candidates, including inhibitors of acetyl-lysine readers (bromodomain-containing proteins), are undergoing ...