The following is a summary of “Histone Modifications and DNA Methylation in Psoriasis: A Cellular Perspective,” published in ...

The most popular of these treatments aim to alter either DNA methylation or histone acetylation. Inhibitors of DNA methylation can reactivate genes that have been silenced. Two examples of these ...

Histone deacetylation and other modifications, particularly the methylation of lysine 9 within histone H3 (H3-K9) residues located in the histone tails, cause chromatin condensation and block ...

Scientists are intensely focused on epigenetic gene regulation because drugs can be developed to target specific histone modifications and switch specific genes "on" and "off." Methylation is one ...

These useful findings assigned a novel functional implication of histone acylation, crotonylation. Although the mechanistic insights have been provided in great detail regarding the role of the YEATS2 ...

Epigenetic alterations have emerged as critical factors in the pathogenesis of brain cancer, particularly gliomas. This article explores the impact of organochlorine pesticides (OCPs) on the ...