High-grade prostatic intraepithelial neoplasia (HGPIN) is the most likely precursor of prostatic adenocarcinoma according to virtually all available evidence. This lesion is characterized by ...
Hosted on MSN29d
A therapeutic HPV vaccine could eliminate precancerous cervical lesions, clinical trial suggestsMore information: Vvax001, a therapeutic vaccine for patients with HPV16-positive high-grade cervical intraepithelial neoplasia: a Phase II trial, Clinical Cancer Research (2025). DOI: 10. ...
Cervical neoplasia is graded by how deeply the cell changes extend through the basement membrane of the cervix. ‘High-grade’ intraepithelial neoplasia means that the lesions affect at least two-thirds ...
Source Reference: Eerkens AL, et al "Vvax001, a therapeutic vaccine for patients with HPV16-positive high-grade cervical intraepithelial neoplasia: a phase II trial" Clin Cancer Res 2025 ...
A therapeutic vaccine targeting human papillomavirus type 16 (HPV16) induced regression in high-grade precancerous ... In those with grade 3 cervical intraepithelial neoplasia (CIN3), cells ...
“Our findings demonstrate that the therapeutic vaccine Vvax001 is safe, well-tolerated, and effective in eradicating HPV16-associated CIN3 lesions and clearing the underlying persistent HPV16 ...
Nat Clin Pract Urol. 2007;4(6):321-332. Blockade of 5α-reductase with drugs such as finasteride does not seem to induce large morphological changes in HGPIN, unlike other forms of androgen ...
A therapeutic vaccine targeting human papillomavirus type 16 (HPV16) induced regression in high-grade precancerous ... In those with grade 3 cervical intraepithelial neoplasia (CIN3), cells ...
Get Instant Summarized Text (Gist) A therapeutic vaccine targeting HPV16 showed promise in reducing high-grade precancerous cervical lesions in a Phase II clinical trial. Among 18 patients with ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback