High-grade prostatic intraepithelial neoplasia (HGPIN) is the most likely precursor of prostatic adenocarcinoma according to virtually all available evidence. This lesion is characterized by ...

Other findings in the prostate might also indicate premalignant disorders, such as low-grade PIN, atrophy, malignancy-associated foci, and atypical adenomatous hyperplasia. The data for such ...

Before it does so, patients may typically exhibit intraepithelial neoplasia, a potentially pre-cancerous change to the cervical cells. Cervical neoplasia is graded by how deeply the cell changes ...

More information: Vvax001, a therapeutic vaccine for patients with HPV16-positive high-grade cervical intraepithelial neoplasia: a Phase II trial, Clinical Cancer Research (2025). DOI: 10. ...

A therapeutic vaccine targeting human papillomavirus type 16 (HPV16) induced regression in high-grade precancerous ... In those with grade 3 cervical intraepithelial neoplasia (CIN3), cells ...

“Our findings demonstrate that the therapeutic vaccine Vvax001 is safe, well-tolerated, and effective in eradicating HPV16-associated CIN3 lesions and clearing the underlying persistent HPV16 ...

A therapeutic vaccine targeting human papillomavirus type 16 (HPV16) induced regression in high-grade precancerous ... In those with grade 3 cervical intraepithelial neoplasia (CIN3), cells ...

Get Instant Summarized Text (Gist) A therapeutic vaccine targeting HPV16 showed promise in reducing high-grade precancerous cervical lesions in a Phase II clinical trial. Among 18 patients with ...