Hepatotoxicity is damage or injury to the liver as a result of damaging or destructive agents such as drugs or industrial chemicals which are termed hepatotoxins. This study reveals that ...

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Recent draft guidance highlights the challenges that industry and regulators face to predict rare drug-induced liver injury. At the end of August 2008, the consultation period ended for comments ...

†Data from lapatanib-treated patients with metastatic breast cancer [43,93]. ‡Data from pazopanib-treated patients with renal cell carcinoma [31]. §This is a definition of a possible Hy's law ...