Hepatotoxicity is damage or injury to the liver as a result of damaging or destructive agents such as drugs or industrial chemicals which are termed hepatotoxins. This study reveals that ...

Recent draft guidance highlights the challenges that industry and regulators face to predict rare drug-induced liver injury. At the end of August 2008, the consultation period ended for comments ...

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Researchers have demonstrated, for the first time in the world using mice, the ability to overcome significant challenges in gene therapy using adeno-associated virus vectors (AAV), specifically ...

Systems and solutions that accelerate drug discovery and development workflows, today announced the launch of its PhysioMimix ...

Even today, 30% of drug candidates fail in clinical trials, and 18% of these failures are attributed to hepatotoxicity concerns 1. Existing methods to assess human drug-induced liver injury (DILI ...