Computational analysis of the variations in the HIV-1 genome sequence that correlate with preferential binding to the CCR5 (C-C-motif receptor 5) or CXCR4 (C-X-C motif receptor 4) coreceptors in ...

Curing HIV will be harder than curing cancer. Apart from a few 'miracle' cases, antiretrovirals only suppress HIV, they don't ...

Once inside human cells, HIV integrates the viral genome into that of the human host. Ultimately, the virus uses our body's machinery to produce copies of itself and spread infection. The HIV-1 ...

He set out to answer this question, and recently published in the Journal of Virology that some of the excised viral DNA molecules form stable DNA circles that can reintegrate into the genome. 3 This ...

but the virus still remains embedded and hidden in the human genome. Seven people are confirmed to have been cured of HIV with a stem cell therapy used to replace all the immune cells in their bodies.

Although several human genetic variants have been implicated in the control and spread of HIV within a host, this is the first time that a sex chromosome has been found to harbor a suspect stretch of ...

Schematic representation of HIV-1 genome organization. The three coding reading frames are depicted along with their open reading frames (rectangles). Genome position is numbered according to HXB2 ...

HIV-1, like other viruses ... was an intricate RNA structure near the critical "frameshift site" in the viral genome. This frameshift site is essential for the virus to produce the correct ...

The aim: to use whole genome sequencing to identify and understand the polymorphism and mutations within individuals of African descent and how they relate to HIV. “We screen participants by ...

HIV drug susceptibility tests can evaluate either the genotype or phenotype of the predominant viral quasispecies. The HIV genotype refers to the actual DNA sequence of the virus; the phenotype ...