近年来，国内外大量研究均已表明，HBV在肝内形成的共价闭合环状DNA（HBV cccDNA）库的持续存在与HBV慢性持续性感染以及慢性乙型肝炎（CHB）难以治愈 ...

Despite numerous treatment advances, chronic hepatitis B virus (HBV) infection remains a largely incurable disease impacting more than 290 million people worldwide. All patients with chronic HBV ...

Viral hepatitis is a major danger to public health. According to WHO’s 2024 Global Hepatitis Report, viral hepatitis deaths ...

Treatment with xalnesiran, a small interfering RNA molecule, plus an immunomodulator resulted in hepatitis B surface antigen loss among adults with chronic HBV infection, according to a study ...

The push to cure hepatitis B kicked off in earnest about 10 years ago, when several leading HBV scientists began convening scientific workshops aimed at developing a cure-focused action plan ...

advances in our understanding of hepatitis B virus (HBV) are helping to bring researchers closer to new solutions, namely a functional cure – that is, undetectable viral markers for a minimum of ...

The American Gastroenterology Association (AGA) updated its clinical practice guidelines for managing hepatitis B ...

Researchers update clinical practice guidelines for how to prevent and monitor hepatitis B virus reactivation.

Five more patients obtained virological response 24 weeks after the end of treatment. ‡Virological response in this study was defined as negative HBV DNA with normal aminotransferases and ...

and HBV DNA after 24 weeks' treatment to below the lower limit of detection in people with chronic hepatitis B, raising hopes that it could offer permanent cure, allowing safe termination of ...