Much of the difficulty of determining the contributions of individual residues to protein structure and function stems from the need to generate and evaluate a large number of mutants. The ...

Functional protein design, particularly for proteins ... complex molecular–protein interactions and capturing sequence-structure dependencies. PocketGen addresses these issues, offering a ...

Evolution has been fine-tuning life at the molecular level for billions of years. Proteins, the fundamental building blocks ...

Proteins are the workhorses that keep our cells running, and there are many thousands of types of proteins in our cells, each ...

The protein was then synthesized and tested in the lab. It glowed—a clear sign of success. The AI had effectively charted a ...

Proteins, the pillars of cellular function, often assemble into “complexes” to fulfill their functions. A study by the University of Geneva (UNIGE) and the Weizmann Institute, in collaboration with ...