Announcing a new publication for Acta Materia Medica journal. Excessive consumption of acetaminophen (APAP) has emerged as ...

2024年5月20日，全国团体标准信息平台发布公告，国内首个基于人源肝脏类器官的药物肝脏毒性评价技术团体标准《基于人源肝脏类器官的药物肝脏毒性评价技术》（标准编号为 T/CRHA 052—2024）正式发布， ...

First identified by Stevens and Johnson in 1922, SJS and TEN are now recognized as disorders with a continuum of severity, from milder forms (SJS) to the most severe (TEN). SJS/TEN is associated with ...

Drug-induced liver injury (DILI) is common because it can be caused by different pharmacological agents from nearly all classes of medications, including hepatotoxic drugs, anesthetics, anticancer ...

The supplement industry is booming—but so are serious health issues tied to taking these pills and powders. Here’s what ...

Although initially studied in cancer, ferroptosis is increasingly implicated in various diseases, including liver injury. However, the liver's robust antioxidant defenses, including glutathione ...

Derisking of drug-induced liver injury (DILI) continues to be a challenge for pharmaceutical scientists. Join Michael Hafey, Principal Scientist at Merck, as he discusses how to utilize a two-tiered ...

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CN Bio has launched its PhysioMimix DILI (drug-induced liver injury) assay kit: Human 24. Based on Cambridge Science Park, CN Bio develops organ-on-a-chip (OOC) systems and solutions that accelerate ...

Existing methods to assess human drug-induced liver injury (DILI) use a combination of data sources, including in vitro assays, in vivo animal studies, and in silico modelling. Current preclinical ...