Cilia drive fluid flow in development and physiology, but this requires that all cilia in a tissue orient the same way. Earlier studies indicated that both planar cell polarity (PCP) signalling ...

By reexamining 3D images used to map the connections between brain cells, researchers are uncovering new information about a small, elusive, and often overlooked cellular appendage.

They provide nanometer-scale views of all the cells and structures in a volume of tissue—including cilia. "Every time you look into these large-scale volume data sets, you are seeing new biology ...