Hughes decided to begin by finding a way to visualize primary cilia on human islets. Over months, she and her collaborators optimized a protocol for peeling away the entire cell membrane to see the ...

The organelle is membrane-bound and contains multiple microtubules running along its length. Whereas primary cilia have relatively little additional structure, motile cilia have both a central ...

Cilia are outgrowths of the plasma membrane of eukaryotic cells that contain a specialised cytoskeleton. Motile cilia are present on multiciliated cells and use this cytoskeleton to move fluid ...

Disruption of photoreceptor cilia has been implicated in a variety ... revealed varying degrees of damage to photoreceptor membrane disks and ciliary axonemes. These results indicate that ...