Researchers found that bioengineered CAR-T cells when mixed with other immune cells can "donate" proteins, suggesting ...

Researchers have discovered stem-like T cells, enabled by ID3 protein, that combat immune exhaustion in chronic diseases.

of the Chinese Academy of Sciences has developed a chimeric antigen receptor T (CAR-T) cell exhaustion model and a functional screening platform for identifying compounds that can rejuvenate ...

Laurie Adami's experience with CAR T-cell therapy highlights its potential in treating Non-Hodgkin Lymphoma, emphasizing the ...

Researchers have identified a rare type of immune cells that hold the key to maintaining long-term immune responses.

Prolonged illnesses like cancer and chronic infections often leave the immune system in a state of exhaustion, where its frontline defenders -- T cells -- lose their ability to function effectively.

The research, led by the Peter Doherty Institute for Infection and Immunity (Doherty Institute) and the Peter MacCallum ...

While CAR T therapy has been transformative in treating certain cancers, its effectiveness can wane over time due to T cell exhaustion. Professor Ricky Johnstone, Executive Director Cancer ...

A discovery about the mechanisms that enable the immune system to sustain long-term protection could revolutionize treatment for chronic disease and cancer.