No doubt 2025 will usher in many more advances in CRISPR therapies, thanks to the FDA’s new Platform Technology Designation ...
Gene therapies based on the CRISPR-Cas system have already been successfully used in clinical practice. In recent years, for example, a hundred patients suffering from the hereditary disease ...
“Almost half of all bacteria and the large majority of archaea on planet Earth have an endogenous CRISPR-Cas system in them,” he said. “One of the great things to do is just to repurpose the ...
A UCO team has applied the genome editing technique, which garnered a Nobel Prize in Chemistry in 2020, to unravel the ...
Biomedical engineers at Duke University have demonstrated a promising new approach that could be used to treat a rare and ...
expanding CRISPRi targeting scope for functional genomics and enabling efficient screening of repeated genomic elements Type I-E CRISPR–Cas system is one of the most extensively studied RNA ...
5,15 Both technologies are based on the CRISPR-Cas system but utilize different CRISPR-associated proteins, Cas13 for SHERLOCK and Cas12a for DETECTR, to achieve their highly specific diagnostic ...
CRISPR-Cas9 genome editing exploits the CRISPR-Cas system to modify a genome in a targeted manner. Guided by RNA, the Cas9 endonuclease breaks DNA at a target sequence. Imprecise repair of the ...
Crispr Therapeutics AG has revenue declines but holds strong financials. Promising Sickle Cell therapy & 2025 data readouts ...
Australian researchers have successfully introduced an improved version of Cas12a gene-editing enzyme in mice.
2020年,詹妮弗·杜德纳(Jennifer A. Doudna)教授与埃马纽埃尔·夏彭蒂耶(Emmanuelle Charpentier)共同荣获诺贝尔化学奖,以表彰她们共同开发了基因组编辑方法CRISPR的卓越贡献。 受Frontiers for Young Minds邀请,杜德纳撰文解释了CRISPR的工作原理以及她与合作者是如何发现这一机制的。杜德纳说, ...
Potent in vivo gene editing in skeletal muscle of non-human primates by a novel, ultracompact CRISPR system delivered via a single AAV vector.