High-speed microscopy reveals real-time protein translocation across a bacterial membrane
Protein translocation is an essential, nano-scale dynamic process that facilitates the movement of proteins across cellular ...
Nature5mon
Traffic control: regulation of kinesin motors
Kinesins contain a conserved motor domain for ATP hydrolysis and microtubule binding, and divergent non-motor domains for family-specific regulatory mechanisms and functions. The regulation of ...
Nature4y
Proteins at the Y-shaped DNA replication fork
A DNA helicase, powered by ATP hydrolysis, propels itself rapidly along one of the template DNA strands (here the lagging strand), forcing open the DNA helix ahead of the replication fork.
Nanowerk10mon
Molecular Motors: Nature's Nanomachines
The motor domain contains the catalytic site for ATP hydrolysis and the actin or microtubule-binding site. The neck region acts as a lever arm, amplifying the small conformational changes generated by ...