This is because proteins form attachments and interact with many other molecules and structures inside organisms. The shape of a protein determines what it can interact with, just like the shape ...

The tiny protein known as transthyretin can cause big problems in the body when it misfolds after secretion. While healthy ...

Crucially, the approach works even with the predicted structures of proteins that have never been experimentally determined. It has implications for the massive amount of structural data being ...

If the NMR data collection for a 120 residue protein takes 4–5 weeks on a 600 MHz spectrometer and if automated data processing takes 1 day, 120 structures can be determined in 1 year by 12 ...

Proteins, the pillars of cellular function, often assemble into “complexes” to fulfill their functions. A study by the ...

Although the rational protein design approach offers an increased possibility of beneficial alterations, it is not easy to accurately predict the sequence-structure-function relationship, particularly ...

More information: Nabin Giri et al, De novo atomic protein structure modeling for cryoEM density maps using 3D transformer ...